Ferrous iron is reacted with glycine to form bis-glycinate chelate, a non-electrically charged compound that is totally nutritionally functional. The absence of electrical charge, uncommon for an iron supplement, makes it less likely that iron bis-glycinate can interfere with absorption of other minerals such as calcium, vitamin E or vitamin C. Iron solubility from iron bis-glycine chelate is not affected by pH changes from 2-6. This means it travels unchanged through the stomach, into the intestine, where it is absorbed and released for transport throughout the body.