SACCHRO250™ is manufactured using a process that involves controlled temperature and low vacuum, eliminating the shock of freeze-drying. The drying procedure, which does not modify the water content of the preparation, slows down aging, cell deterioration, and contamination, leading to increased stability and greater resistance to gastric acid. This process does not require or contain dairy products or lactose.

Saccharomyces boulardii (S boulardii) is a natural, non-pathogenic yeast that may help support and maintain the healthy ecology of the small and large intestines.